Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore
Stronen, Astrid Vik; Jedrzejewska, Bogumila; Pertoldi, Cino; Demontis, Ditte; Randi, Ettore; Niedzialkowska, Magdalena; Borowik, Tomasz; Sidorovich, Vadim E.; Kusak, Josip; Kojola, Ilpo; Karamanlidis, Alexandros A.; Ozolins, Janis; Dumenko, Vitalii; Czarbinsja, Sylwia D. (2015)
Stronen, Astrid Vik
Jedrzejewska, Bogumila
Pertoldi, Cino
Demontis, Ditte
Randi, Ettore
Niedzialkowska, Magdalena
Borowik, Tomasz
Sidorovich, Vadim E.
Kusak, Josip
Kojola, Ilpo
Karamanlidis, Alexandros A.
Ozolins, Janis
Dumenko, Vitalii
Czarbinsja, Sylwia D.
Julkaisusarja
Ecology and evolution
Volyymi
5
Numero
19
Sivut
p. 4410-4425
Wiley
2015
by
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2045-7758/homepage/open_access_license_and_copyright.htm
All Ecology and Evolution articles are published under the terms of the Creative Commons Attribution License (CC BY) which allows users to copy, distribute and transmit an article, adapt the article and make commercial use of the article. The CC BY license permits commercial and non-commercial re-use of an open access article, as long as the author is properly attributed.
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2045-7758/homepage/open_access_license_and_copyright.htm
All Ecology and Evolution articles are published under the terms of the Creative Commons Attribution License (CC BY) which allows users to copy, distribute and transmit an article, adapt the article and make commercial use of the article. The CC BY license permits commercial and non-commercial re-use of an open access article, as long as the author is properly attributed.
Julkaisun pysyvä osoite on
http://urn.fi/URN:NBN:fi-fe2016092724402
http://urn.fi/URN:NBN:fi-fe2016092724402
Tiivistelmä
Ecological and environmental heterogeneity can produce genetic differentiation in highly mobile species. Accordingly, local adaptation may be expected across comparatively short distances in the presence of marked environmental gradients. Within the European continent, wolves (Canis lupus) exhibit distinct north-south population differentiation. We investigated more than 67-K single nucleotide polymorphism (SNP) loci for signatures of local adaptation in 59 unrelated wolves from four previously identified population clusters (northcentral Europe n=32, Carpathian Mountains n=7, Dinaric-Balkan n=9, Ukrainian Steppe n=11). Our analyses combined identification of outlier loci with findings from genome-wide association study of individual genomic profiles and 12 environmental variables. We identified 353 candidate SNP loci. We examined the SNP position and neighboring megabase (1Mb, one million bases) regions in the dog (C. lupus familiaris) genome for genes potentially under selection, including homologue genes in other vertebrates. These regions included functional genes for, for example, temperature regulation that may indicate local adaptation and genes controlling for functions universally important for wolves, including olfaction, hearing, vision, and cognitive functions. We also observed strong outliers not associated with any of the investigated variables, which could suggest selective pressures associated with other unmeasured environmental variables and/or demographic factors. These patterns are further supported by the examination of spatial distributions of the SNPs associated with universally important traits, which typically show marked differences in allele frequencies among population clusters. Accordingly, parallel selection for features important to all wolves may eclipse local environmental selection and implies long-term separation among population clusters.
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